Tebuconazole is a triazole fungicide introduced into the market by Bayer. It has excellent biological activity, low dosage, strong systemicity, and a wide range of applications. It is resistant to powdery mildew, stalk rust fungus, ceratocystis, Diseases caused by Sclerotium and Needle spores can be effectively prevented.
Synthesis of Tebuconazole Technical:
The current tebuconazole process mainly consists of the following processes:
1) Synthesis of 4,4-Dimethyl-1-(4-chlorophenyl)-3-pentanone (“pentanone” for short) through pinacolone and p-chlorobenzaldehyde
2) Cyclization of pentanone to obtain ethylene oxide derivatives;
3) Tebuconazole is obtained from ethylene oxide derivatives and triazole.
In the above reaction process, pentanone is a core intermediate. At present, some companies rely on outsourcing. At the same time, the main raw materials for pentanone synthesis, pinacolone and p-chlorobenzaldehyde, have a large market price fluctuation, which leads to the tension of pentanone supply.
Beijing Yibai Biotechnology Co., Ltd is producing pentanone now, regular stable stock ecch month is 50MT.
Post time: Aug-31-2020