High Purity USP BP EP 59-05-2 Methotrexate for Tumour Treatment

Short Description:

  • Purity: ≧99.0% Yellow crystalline powder
  • Quality Standards: USP/BP/EP/IP
  • Certificate: ISO, GMP, COA, MOA, MSDS, etc
  • Capacity: 150Kg Per Month
  • Shelf Life: Three Years
  • Application: A class of drugs known as anti-metabolites
  • Team Advantage: Experienced export sales team with professional training in factory
  • Product Detail


    Product Tags

    Product name Methotrexate
    Synonyms (+)-Amethopterin; (+)-4-Amino-10-methylfolic acid; N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamic acid
    CAS No. 59-05-2
    Appearance Yellow crystalline powder
    Molecular Formula C20H22N8O5
    Molecular Weight 454.44
    Application Medicine grade or research purpose
    Packing As per your request
    Storage Preserve in tight,light-resistant containers in a cool place


    Certificate of Analysis Test according to: EP9.0

    Methotrexate CAS No.: 59-05-2




    Appearance Yellow or orange, crystalline, hygroscopic powder Complies
    Identification IR;UV Complies
    Solubility Practically insoluble in water, in ethanol(96%) and in methylene chloride. It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxides and carbonates. Complies
    Water ≤13% 11.8%
    Related Substances Impurity B≤0.3%Impurity C≤0.5%Impurity E≤0.3%Impurity H≤0.2%Impurity I≤0.2%Unspecified Impurities≤0.05%

    Sum of impurities other than B,C&E≤0.5%



    Enantiomeric Purity ≤3.0% 1.6%
    Heavy Metals ≤20ppm  Complies
    Sulphated Ash ≤0.1% 0.07%
    Residual Solvents Ethyl ether≤500ppmAcetone≤1000ppmEthanol≤ 2000ppm 20ppm63ppm48ppm
    Assay 97.0~102.0% 99.49%


    Certificate of Analysis Test according to: USP32

    Methotrexate CAS No.: 59-05-2




    CHARACTERISTICS Yellow crystalline powder Complies
    IDENTIFICATION IR. UV Conform Complies
    WATER ≤12%  10.8%
    RESIDUE ON IGNITION ≤0.1% 0.07%
    Chromatographic purity Single impurity:≤0.5% 0.27%
    Total Impurities:≤2.0 % 0.73%
    SPECIFIC ROTATION  Between  +19°to +24°  +21.25°
    ASSAY 98.0~102.0% 99.27%

    Company Information

    √ Management layer’s full experience in factory and skilled technicians followers;
    √ Quality is always our top consideration, Strict QC system;
    √ 11 years experienced exporting sales team;
    √ Independent R&D lab;
    √ Two signed long term GMP workshops;
    √ Rich resources of plenty idle factories for customized project;
    √ High Efficiency working team with consistent path.

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