High definition Methotrexate Sodium - High Purity USP BP EP 59-05-2 Methotrexate for Tumour Treatment – Yibai

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High definition Methotrexate Sodium - High Purity USP BP EP 59-05-2 Methotrexate for Tumour Treatment – Yibai Detail:

Product name	Methotrexate
Synonyms	(+)-Amethopterin; (+)-4-Amino-10-methylfolic acid; N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamic acid
CAS No.	59-05-2
Appearance	Yellow crystalline powder
Molecular Formula	C₂₀H₂₂N₈O₅
Molecular Weight	454.44
Application	Medicine grade or research purpose
Packing	As per your request
Storage	Preserve in tight,light-resistant containers in a cool place

Certificate of Analysis Test according to: EP9.0 Methotrexate CAS No.: 59-05-2
ITEMS	STANDARDS	RESULTS
Appearance	Yellow or orange, crystalline, hygroscopic powder	Complies
Identification	IR;UV	Complies
Solubility	Practically insoluble in water, in ethanol(96%) and in methylene chloride. It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxides and carbonates.	Complies
Water	≤13%	11.8%
Related Substances	Impurity B≤0.3%Impurity C≤0.5%Impurity E≤0.3%Impurity H≤0.2%Impurity I≤0.2%Unspecified Impurities≤0.05% Sum of impurities other than B,C&E≤0.5%	0.04%0.45%0.03%NDND0.02% 0.04%
Enantiomeric Purity	≤3.0%	1.6%
Heavy Metals	≤20ppm	Complies
Sulphated Ash	≤0.1%	0.07%
Residual Solvents	Ethyl ether≤500ppmAcetone≤1000ppmEthanol≤ 2000ppm	20ppm63ppm48ppm
Assay	97.0～102.0%	99.49%

Certificate of Analysis Test according to: USP32 Methotrexate CAS No.: 59-05-2
ITEMS	STANDARDS	RESULTS
CHARACTERISTICS	Yellow crystalline powder	Complies
IDENTIFICATION	IR. UV Conform	Complies
WATER	≤12%	10.8%
RESIDUE ON IGNITION	≤0.1%	0.07%
Chromatographic purity	Single impurity：≤0.5%	0.27%
Chromatographic purity	Total Impurities：≤2.0 %	0.73%
SPECIFIC ROTATION	Between +19°to +24°	+21.25°
ASSAY	98.0～102.0%	99.27%

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